Old Main is once again the premier classroom building on campus. While retaining many of the classic features of a bygone era, the building functions as one of the most modern academic buildings at the University. Its new climate control and security systems are the best on campus, and the entire building is wired with fiber-optic cable to link Old Main with the campus' computer network.

It is home to the Fulbright College of Arts and Sciences. Housed in the building are the Dean's office, the Fulbright Honors Program, Giffels Auditorium, and the departments of anthropology, history, philosophy, political science, and sociology.